<a href=http://stromectol.autos/>ivermectin brand name</a> a providing MSNs or exMSNs as prepared in any of the above mentioned methods; b loading a first bioactive ingredient by contacting the MSNs or exMSNs with the first bioactive ingredient; c loading a second bioactive ingredient by contacting the MSNs or exMSNs loaded with the first bioactive ingredient; and d optionally, repeating step c for loading further bioactive ingredient s by independently and successively contacting the MSNs or exMSNs loaded with bioactive ingredients with the further bioactive ingredient s